- 专利标题： Anti eotaxin-2 antibodies that recognize additional CCR3-binding chemokines
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申请号： US15122241申请日： 2015-03-04
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公开(公告)号： US10246508B2公开(公告)日： 2019-04-02
- 发明人: Adi Mor
- 申请人： CHEMOMAB LTD.
- 申请人地址： IL Tel Aviv
- 专利权人： CHEMOMAB LTD.
- 当前专利权人： CHEMOMAB LTD.
- 当前专利权人地址： IL Tel Aviv
- 代理机构： Vorys, Sater, Seymour and Pease LLP
- 国际申请： PCT/IL2015/050234 WO 20150304
- 国际公布： WO2015/132790 WO 20150911
- 主分类号： C07K16/24
- IPC分类号： C07K16/24 ; C07H21/04 ; C12N15/85 ; A61K39/00
摘要：
Provided are isolated polyspecific antibodies directed to a unique epitope in the chemokine eotaxin 2. The antibodies bind additional CCR3-binding chemokines. Further provided are methods for using of the antibodies for attenuating the migration of various cells and for treating fibrotic diseases, autoimmune inflammatory disorders, monocyte related disorders or allergic atopic disorders.
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