The application discloses a multi-station wheel burr removing device, includes lifting translation systems, a clamping drive system and grinding systems. In practical use, the four V-shaped rollers clamp a wheel, a sixth servo motor and the first electric servo cylinder respectively adjusts the angle and the position of the rolling brush, and when the rolling brush contacts the edge of a wheel flange, burrs can be removed; the fifth servo motor and the sixth servo motor respectively adjusts the position and the angle of the lower grinding head, and when the lower grinding head contacts a wheel valve hole, burrs below can be removed; the third servo motor and the second electric servo cylinder respectively adjusts the angle and the position of the upper grinding head, when the upper grinding head contacts the wheel valve hole, burrs can be removed.