Invention Grant
- Patent Title: Carbazole derivatives
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Application No.: US15521194Application Date: 2015-10-23
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Publication No.: US10266491B2Publication Date: 2019-04-23
- Inventor: Saleem Ahmad , Douglas G. Batt , Qingjie Liu , John E. Macor , Joseph A. Tino , Scott Hunter Watterson , Satheesh Kesavan Nair , Tarun Kumar Maishal
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Gary Greenblatt
- International Application: PCT/US2015/057077 WO 20151023
- International Announcement: WO2016/065236 WO 20160428
- Main IPC: C07D401/04
- IPC: C07D401/04 ; C07D209/88 ; A61K31/4523 ; C07D403/04 ; C07D471/04 ; C07D401/06 ; C07D403/06 ; C07D403/12 ; C07D471/10 ; C07D487/04 ; C07D495/04

Abstract:
Disclosed are compounds of Formula (I): (I) or a salt thereof, wherein Q, R1a, R1b, R2a, R2b, R3, R4, R5a, R5b, R6a, R6c, R7a, R7b, R7c, and R7d are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
Public/Granted literature
- US20170362176A1 CARBAZOLE DERIVATIVES Public/Granted day:2017-12-21
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