Invention Grant
- Patent Title: Phenyl quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors
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Application No.: US15977512Application Date: 2018-05-11
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Publication No.: US10266495B2Publication Date: 2019-04-23
- Inventor: Jian Lin , Anna Ericsson , Ann-Marie Campbell , Gary Gustafson , Zhongguo Wang , R. Bruce Diebold , Susan Ashwell , David R. Lancia, Jr. , Justin Andrew Caravella , Wei Lu
- Applicant: FORMA TM2, Inc.
- Applicant Address: US MA Watertown
- Assignee: FORMA TM2, INC.
- Current Assignee: FORMA TM2, INC.
- Current Assignee Address: US MA Watertown
- Agency: Choate, Hall & Stewart LLP
- Agent John P. Rearick; Christopher K. Haley
- Main IPC: C07D215/227
- IPC: C07D215/227 ; A61K31/4709 ; C07D401/12 ; C07D405/12 ; C07D409/12 ; C07D471/04
Abstract:
The invention relates to inhibitors of mutant isocitrate dehydrogenase (mt-IDH) proteins with neomorphic activity useful in the treatment of cell-proliferation disorders and cancers, having the Formula: where A, B, W1, W2, W3, and R1-R8 are described herein.
Public/Granted literature
- US20180327361A1 PHENYL QUINOLINONE DERIVATIVES AS MUTANT-ISOCITRATE DEHYDROGENASE INHIBITORS Public/Granted day:2018-11-15
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