- Patent Title: Bile acid analogs as FXR/TGR5 agonists and methods of use thereof
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Application No.: US14934122Application Date: 2015-11-05
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Publication No.: US10266560B2Publication Date: 2019-04-23
- Inventor: Yat Sun Or , Guoqiang Wang , Ruichao Shen , Xuechao Xing
- Applicant: Enanta Pharmaceuticals, Inc.
- Applicant Address: US MA Watertown
- Assignee: ENANTA PHARMACEUTICALS, INC.
- Current Assignee: ENANTA PHARMACEUTICALS, INC.
- Current Assignee Address: US MA Watertown
- Agency: Elmore Patent Law Group, P.C.
- Agent Edgar W. Harlan; Carolyn S. Elmore, Esq.
- Main IPC: A61K31/56
- IPC: A61K31/56 ; A61K31/58 ; C07J41/00 ; C07J43/00

Abstract:
The present invention relates to compounds of Formula (I), and pharmaceutically acceptable salts thereof, where R1, R2, R3, R4, R5, R6, R7, R8 and m are as defined herein, pharmaceutical compositions comprising these compounds and methods of use of these compounds for treating a TGR5 mediated disease or condition.
Public/Granted literature
- US20160130297A1 BILE ACID ANALOGS AS FXR/TGR5 AGONISTS AND METHODS OF USE THEREOF Public/Granted day:2016-05-12
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