Invention Grant
- Patent Title: Dual receptor antagonistic antigen-binding proteins and uses thereof
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Application No.: US15247792Application Date: 2016-08-25
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Publication No.: US10266598B2Publication Date: 2019-04-23
- Inventor: Huiquan Han , Xiaolan Zhou , Qing Chen , Mei-Mei Tsai
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Lisa E. Alexander
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K16/46 ; A61K39/00 ; C07K16/42
Abstract:
This disclosure relates to antagonistic dual receptor antigen-binding proteins, e.g. antibodies and methods of using the dual receptor antibodies for treatment of pathological diseases. The dual receptor antibodies may comprise an antibody to ActRII receptors and may be used to treat pathological condition. The pathological conditions can comprise muscle wasting diseases or any disease that requires stimulation of muscle growth.
Public/Granted literature
- US20170107288A1 Dual receptor antagonistic antigen-binding proteins and uses thereof Public/Granted day:2017-04-20
Information query
