A power supply system includes a control module for generating a control signal; a first charging pump module, coupled to the control module, for generating an adjustment charging value according to the control signal, and outputting a charging voltage according to the adjustment charging value and a conduction voltage source; an amplifying module, coupled to the first charging pump module, for utilizing the charging voltage to generate an amplifying voltage; and a load module, coupled to the amplifying module, for processing a dynamic charging operation according to the amplifying voltage.