Invention Grant
- Patent Title: Compositions and methods relating to myomaker-induced muscle cell fusion
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Application No.: US14900005Application Date: 2014-06-27
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Publication No.: US10272137B2Publication Date: 2019-04-30
- Inventor: Eric Olson , Douglas P. Millay
- Applicant: The Board of Regents of the University of Texas System
- Applicant Address: US TX Austin
- Assignee: The Board of Regents of the University of Texas System
- Current Assignee: The Board of Regents of the University of Texas System
- Current Assignee Address: US TX Austin
- Agency: Parker Highlander PLLC
- International Application: PCT/US2014/044554 WO 20140627
- International Announcement: WO2014/210448 WO 20141231
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/17 ; A61K45/06 ; C07K14/47 ; A61K9/00 ; C12N5/16 ; C12N15/02
Abstract:
The present disclosure describes the fusogenic activity of the Myomaker protein. This polypeptide, when expressed in non-muscle cells, is able to drive fusion of the cell with a muscle cell, but not with other non-muscle cells. The use of this protein and cell expressing it in the delivery of exogenous genetic material to muscle cells also is described.
Public/Granted literature
- US20160136240A1 COMPOSITIONS AND METHODS RELATING TO MYOMAKER-INDUCED MUSCLE CELL FUSION Public/Granted day:2016-05-19
Information query
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