Invention Grant
- Patent Title: Imidazopyridazine compounds useful as modulators of IL-12, IL-23 and/or IFN-α responses
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Application No.: US15102991Application Date: 2014-12-10
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Publication No.: US10273237B2Publication Date: 2019-04-30
- Inventor: Chunjian Liu , James Lin , Ryan M. Moslin , David S. Weinstein , John S. Tokarski
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Elliott Korsen
- International Application: PCT/US2014/069476 WO 20141210
- International Announcement: WO2015/089143 WO 20150618
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D487/14 ; C07D498/14

Abstract:
Compounds having the following formula (I), or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.
Public/Granted literature
- US20160304524A1 IMIDAZOPYRIDAZINE COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN-ALPHA RESPONSES Public/Granted day:2016-10-20
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