Invention Grant
- Patent Title: PCSK9 peptide vaccine conjugated to a Qbeta carrier and methods of using the same
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Application No.: US15118143Application Date: 2015-02-11
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Publication No.: US10279019B2Publication Date: 2019-05-07
- Inventor: Alan Remaley , John T. Schiller , Marcelo Amar , Bryce Chackerian
- Applicant: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES , STC.UNM
- Applicant Address: US NM Albuquerque
- Assignee: STC.UNM
- Current Assignee: STC.UNM
- Current Assignee Address: US NM Albuquerque
- Agency: Mueting, Raasch & Gebhardt, P.A.
- International Application: PCT/US2015/015408 WO 20150211
- International Announcement: WO2015/123291 WO 20150820
- Main IPC: C07K11/00
- IPC: C07K11/00 ; A61K38/10 ; A61K39/00 ; A61P9/10 ; C12N9/64 ; A61K45/06 ; A61K47/69 ; C07K14/47
Abstract:
A vaccine construct comprising an antigenic PCSK9 peptide and an immunogenic carrier, and methods of using the same that are effective to lower blood cholesterol levels in a mammal and treat dyslipidemias and related disease states in a mammal without the frequency of administration required by passive immunity strategies.
Public/Granted literature
- US20170189503A1 PCSK9 VACCINE AND METHODS OF USING THE SAME Public/Granted day:2017-07-06
Information query
