- 专利标题: Stable liquid pharmaceutical composition based on trazodone
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申请号: US12667694申请日: 2008-07-22
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公开(公告)号: US10292931B2公开(公告)日: 2019-05-21
- 发明人: Marcello Marchetti , Francesca Mariotti , Lorella Ragni , Paolo Scarpetti , Mauro Valenti
- 申请人: Marcello Marchetti , Francesca Mariotti , Lorella Ragni , Paolo Scarpetti , Mauro Valenti
- 申请人地址: IT Rome
- 专利权人: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A.
- 当前专利权人: AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A.
- 当前专利权人地址: IT Rome
- 代理机构: Oblon, McClelland, Maier & Neustadt, L.L.P.
- 优先权: ITMI2007A1573 20070731
- 国际申请: PCT/EP2008/059605 WO 20080722
- 国际公布: WO2009/016069 WO 20090205
- 主分类号: A61K31/496
- IPC分类号: A61K31/496 ; A61P25/24 ; A61K9/00 ; A61K31/495 ; A61K47/10
摘要:
A stable liquid pharmaceutical composition comprising an aqueous solution of a pharmaceutically acceptable salt of acid addition of trazodone, characterized in that said pharmaceutical composition has a pH value between 5.0 and 6.0, and comprises at least two cosolvents selected from the group comprising glycols and polyglycols.
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