There is provided a physiological detection system including a physiological detection device and a host. The physiological detection device is configured to transmit a physiological data series to the host according to a local oscillation frequency. The host is configured to calculate a physiological value according to the physiological data series and determine a correction parameter according to a receiving data parameter and a reference data parameter, wherein the correction parameter is configured to correct the physiological value, process the physiological data series or adjust the local oscillation frequency of the physiological detection device.