A mouse-type rehabilitation exercise device includes a mouse body on which a hand is mounted, a wheel moving the mouse body, a first motor aligning a position of the wheel such that the mouse body moves to a desired direction, a second motor rotating the wheel such that the wheel aligned by the first motor moves to a desired position, a clutch disposed between the second motor and the wheel to enable and disable a power transmitting to the wheel from the second motor, and a controller controlling a driving of the first motor, the second motor, and the clutch.