A method and an apparatus for determining a physical address are disclosed. According to the present disclosure, a page size is obtained according to the higher-order N bits of a linear address, where N is greater than 0 and less than a quantity of bits of the linear address; an index number of a translation lookaside buffer TLB is obtained according to the page size; a mask is obtained according to the page size and a supported minimum page size; a label of the TLB is obtained according to the mask; the higher-order MAC1 bits of a physical address corresponding to the linear address are obtained by searching the TLB according to the index number and the label; and the physical address is obtained according to the mask, the supported minimum page, and the higher-order MAC1 bits of the physical address.