Invention Grant
- Patent Title: Cosmetic composition for preventing or ameliorating hypersensitive skin comprising cedrol or derivatives thereof, or pharmaceutically acceptable salts thereof
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Application No.: US15945601Application Date: 2018-04-04
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Publication No.: US10307383B2Publication Date: 2019-06-04
- Inventor: Ha Won Kim , Dong Hee Lee
- Applicant: University of Seoul Industry Cooperation Foundation
- Applicant Address: KR Seoul
- Assignee: UNIVERSITY OF SEOUL INDUSTRY COOPERATION FOUNDATION
- Current Assignee: UNIVERSITY OF SEOUL INDUSTRY COOPERATION FOUNDATION
- Current Assignee Address: KR Seoul
- Agency: Lucas & Mercanti, LLP
- Priority: KR10-2017-0044176 20170405; KR10-2017-0076435 20170616
- Main IPC: A61K31/045
- IPC: A61K31/045 ; A61K31/015 ; A61P17/06 ; A61P17/04 ; A61P37/00 ; A61K31/075 ; A61K31/12 ; A61K31/215 ; A61K31/336
Abstract:
The present invention relates to a pharmaceutical composition for preventing or treating autoimmune diseases having cedrol or a pharmaceutically acceptable salt thereof as an active ingredient. Particularly, the cedrol or the derivative thereof of the present invention inhibits the expression of IL-17A, and in particular, cedrol, cedryl acetate, and cedrene exhibit the effect of delaying the outbreak of psoriasis and treating thereof in a psoriasis animal model. Therefore, these compounds can be used for the treatment of autoimmune diseases mediated by IL-17.
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