Water treatment systems and associated methods are generally described. Certain embodiments of the water treatment systems and methods described herein may be used to treat water comprising one or more contaminants (e.g., oil, grease, suspended solids, scale-forming ions, volatile organic material) to remove at least a portion of the one or more contaminants. In some embodiments, at least a portion of the treated water may be used directly in certain applications (e.g., oil and/or gas extraction processes). In some embodiments, at least a portion of the treated water may undergo desalination to produce substantially pure water and/or concentrated brine.