- Patent Title: Piperidine oxadiazole and thiadiazole orexin receptor antagonists
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Application No.: US15523251Application Date: 2015-09-27
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Publication No.: US10308645B2Publication Date: 2019-06-04
- Inventor: Nigel Liverton , Scott D. Kuduk , Yunfu Luo , Na Meng , Tingting Yu
- Applicant: MERCK SHARP & DOHME CORP.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent J. Eric Thies; John C. Todaro
- Priority: CNPCT/CN2014/089932 20141030
- International Application: PCT/US2015/057437 WO 20150927
- International Announcement: WO2016/069510 WO 20160506
- Main IPC: C07D413/04
- IPC: C07D413/04 ; C07D413/14 ; C07D417/14 ; C07D417/04
Abstract:
The present invention is directed to piperidine oxadiazole and thiadiazole orexin compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
Public/Granted literature
- US20170313693A1 PIPERIDINE OXADIAZOLE AND THIADIAZOLE OREXIN RECEPTOR ANTAGONISTS Public/Granted day:2017-11-02
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