A system and method of performing speculative parallel execution of a cache line unaligned load instruction including speculatively predicting whether a load instruction is unaligned with a cache memory, marking the load instruction as unaligned and issuing the instruction to a scheduler, dispatching the unaligned load instruction in parallel to first and second load pipelines, determining corresponding addresses for both load pipelines to retrieve data from first and second cache lines incorporating the target load data, and merging the data retrieved from both load pipelines. Prediction may be based on matching an instruction pointer of a previous iteration of the load instruction that was qualified as actually unaligned. Prediction may be further based on using a last address and a skip stride to predict a data stride between consecutive iterations of the load instruction. The addresses for both loads are selected to incorporate the target load data.