An apparatus for controlling an Uplink (UL) power in a wireless communication system including a transmitter/receiver and a controller may be provided. The transmitter/receiver may receive/decode Downlink (DL) data, transmit a feedback signal with respect to the DL data, and receive Transmit power Control (TPC) commands from active set cells including a serving cell. The controller may decode the TPC commands to generate a combined TPC command, in which decoded TPC commands of the active set cells are combined, and calculate a transmission error rate of an UL feedback transmission signal and a requested rate of transmit power increase of the serving cell, determine a transmit power gain offset and the requested rate of transmit power increase, determine an UL power for transmitting a feedback signal with respect to the received DL data based on the transmit power gain offset, and transmit the feedback signal based on the UL power.