Embodiments of the present invention provide a radio bearer setup method, including: establishing, by a base station, an SRB with UE according to a configuration parameter of the SRB, and establishing, according to configuration parameters of N DRBs that carry N services, the N DRBs with the UE, where N≥2, N is an integer, M of the N DRBs occupy different transmission channels and different physical channels, 2≤M≤N, M is an integer, and a transmission channel and a physical channel occupied by the SRB are different from a transmission channel and a physical channel occupied by at least one of the N DRBs. In this way, interruption in all service data between the UE and the base station and a call drop in a communication connection are avoided.