Invention Grant
- Patent Title: Polynucleotides encoding low density lipoprotein receptor
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Application No.: US15026945Application Date: 2014-10-03
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Publication No.: US10323076B2Publication Date: 2019-06-18
- Inventor: Jeff Lynn Ellsworth , Joseph Beene Bolen , Francine M. Gregoire , Justin Guild
- Applicant: ModernaTX, Inc.
- Applicant Address: US MA Cambridge
- Assignee: ModernaTX, Inc.
- Current Assignee: ModernaTX, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Cooley LLP
- Agent Carol D. Laherty; William T. Christiansen, II
- International Application: PCT/US2014/058967 WO 20141003
- International Announcement: WO2015/051214 WO 20150409
- Main IPC: C07K14/705
- IPC: C07K14/705 ; A61K38/00
Abstract:
The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotide molecules encoding low density lipoprotein receptor comprising at least one mutation (e.g., an LDLR signally enhancing mutation).
Public/Granted literature
- US20160244501A1 Polynucleotides Encoding Low Density Lipoprotein Receptor Public/Granted day:2016-08-25
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