发明授权
- 专利标题： Soluble mediator
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申请号： US15975591申请日： 2018-05-09
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公开(公告)号： US10328124B2公开(公告)日： 2019-06-25
- 发明人: Esther Bandala Sanchez , James Dromey , Leonard Charles Harrison , Yuxia Zhang
- 申请人： The Walter and Eliza Hall Institute of Medical Research
- 申请人地址： AU Parkville
- 专利权人： The Walter and Eliza Hall Institute of Medical Research
- 当前专利权人： The Walter and Eliza Hall Institute of Medical Research
- 当前专利权人地址： AU Parkville
- 代理机构： Bozicevic, Field & Francis LLP
- 代理商 Shweta Chandra
- 主分类号： A61K38/10
- IPC分类号： A61K38/10 ; A61K38/17 ; C07K14/705 ; C12N5/0783 ; C07K16/18 ; C12Q1/6883 ; G01N33/50 ; G01N33/68 ; A61K47/68 ; A61K48/00
摘要：
The present disclosure relates to a soluble CD52 glycoprotein and its use in treating diseases regulated by effector T-cells, for example autoimmune diseases such as type 1 diabetes. The present disclosure also relates to fusion proteins comprising the soluble glycoprotein, to cells expressing high levels of CD52, and to diagnostic methods based on the detection of CD52 expression levels in a subject.
公开/授权文献
- US20180256679A1 Soluble Mediator 公开/授权日：2018-09-13
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