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US10336749B2 Method for the preparation of (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1-6-naphthyridine-3-carboxamide and the purification thereof for use as an active pharmaceutical ingredient 有权

  • 专利标题： Method for the preparation of (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1-6-naphthyridine-3-carboxamide and the purification thereof for use as an active pharmaceutical ingredient
  • 申请号： US15753849
    申请日： 2016-08-18
  • 公开(公告)号： US10336749B2
    公开(公告)日： 2019-07-02
  • 发明人: Johannes Platzek
  • 申请人： BAYER PHARMA AKTIENGESELLSCHAFT
  • 申请人地址： DE Berlin
  • 专利权人： BAYER PHARMA AKTIENGESELLSCHAFT
  • 当前专利权人： BAYER PHARMA AKTIENGESELLSCHAFT
  • 当前专利权人地址： DE Berlin
  • 代理机构： Ice Miller LLP
  • 优先权： EP15182043 20150821
  • 国际申请： PCT/EP2016/069558 WO 20160818
  • 国际公布： WO2017/032673 WO 20170302
  • 主分类号： C07D471/04
  • IPC分类号： C07D471/04
Method for the preparation of (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1-6-naphthyridine-3-carboxamide and the purification thereof for use as an active pharmaceutical ingredient
摘要：
The present invention relates to a novel and improved process for preparing (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide of the formula (I)
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