A heavy duty pneumatic tire includes a tread including a pair of central portions, a pair of middle portions and a pair of shoulder portions, wherein each of the portions has an axial width varying periodically while increasing and decreasing in a circumferential direction of the tire. Each of the central portions includes a central block with a hexagonal shaped top face and a central sipe. A total that is the sum of each maximum axial width of the central portions, each maximum axial width of the middle portions, each maximum axial width of the shoulder portions, a maximum axial length of the central sipe provided on one of the central portions, and a maximum axial length of the central sipe provided on the other one of the central portions is in a range of from 1.05 to 1.31 times a tread width.