- 专利标题: Compositions and methods of targeting mutant K-ras
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申请号: US15874485申请日: 2018-01-18
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公开(公告)号: US10344026B2公开(公告)日: 2019-07-09
- 发明人: Chunlin Tao , Laxman Nallan , David G. Ho , Qinwei Wang , Paul Weingarten , Anna B. Juncker-Jensen
- 申请人: NANTBIO, INC.
- 申请人地址: US CA Culver City
- 专利权人: NantBio, Inc.
- 当前专利权人: NantBio, Inc.
- 当前专利权人地址: US CA Culver City
- 代理机构: Lucas & Mercanti, LLP
- 主分类号: A61P35/00
- IPC分类号: A61P35/00 ; C07D417/14
摘要:
Compounds and compositions are presented that inhibit K-Ras, and especially mutant K-Ras. Certain compounds preferentially or even selectively inhibit specific forms of mutant K-Ras, and particularly the G12D mutant form.
公开/授权文献
- US20180201610A1 COMPOSITIONS AND METHODS OF TARGETING MUTANT K-RAS 公开/授权日:2018-07-19
信息查询
IPC分类:
A | 人类生活必需 |
A61 | 医学或兽医学;卫生学 |
A61P | 化合物或药物制剂的特定治疗活性 |
A61P35/00 | 抗肿瘤药 |