An example method includes selecting, based at least on first and second policies, first and second containers in which to execute first and second applications, respectively. The example method further includes isolating execution of the first application in the first container, and isolating execution of the second application in the second container. The example method also includes applying, based at least on the first policy, a first group of security controls to the first application executing in the first container, wherein the first container defines a first domain in which the first application is executed, and applying, based at least on the second policy, a second group of security controls to the second application executing in the second container, wherein the second container defines a second domain in which the second application is executed.