Invention Grant
![Pyrazolo[3,4-b]pyridines and imidazo[1,5-b]pyridazines as PDE1 inhibitors](/docs/US/2019-07-16/US10351561B2/abs.jpg.600x600.jpg)
- Patent Title: Pyrazolo[3,4-b]pyridines and imidazo[1,5-b]pyridazines as PDE1 inhibitors
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Application No.: US15849798Application Date: 2017-12-21
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Publication No.: US10351561B2Publication Date: 2019-07-16
- Inventor: Jan Kehler , Lars Kyhn Rasmussen , Morten Langgard , Mikkel Jessing , Paulo Jorge Vieira Vital , Karsten Juhl , Mauro Marigo
- Applicant: H. Lundbeck A/S
- Applicant Address: DK Valby
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Valby
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: DK201600784 20161222; DK201700404 20170706
- Main IPC: A61K31/4162
- IPC: A61K31/4162 ; A61K31/4188 ; A61K31/437 ; A61K31/5025 ; C07D471/04 ; C07D487/04 ; A61P25/28 ; A61P25/18 ; A61P25/00 ; A61P25/16 ; C07D519/00
![Pyrazolo[3,4-b]pyridines and imidazo[1,5-b]pyridazines as PDE1 inhibitors](/abs-image/US/2019/07/16/US10351561B2/abs.jpg.150x150.jpg)
Abstract:
The present invention provides compounds of formula (I) that are PDE1 enzyme inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders. The present invention also provides pharmaceutical compositions comprising compounds of the invention and methods of treating disorders using the compounds of the invention.
Public/Granted literature
- US20180179200A1 PYRAZOLO[3,4-b]PYRIDINES AND IMIDAZO[1,5-b]PYRIDAZINES AS PDE1 INHIBITORS Public/Granted day:2018-06-28
Information query
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