Invention Grant
- Patent Title: Methods of treating inflammation with IL-17A/F and IL-23P19 bispecific antibodies
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Application No.: US15694374Application Date: 2017-09-01
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Publication No.: US10358490B2Publication Date: 2019-07-23
- Inventor: Brenda L. Stevens , Alison Witte , Mark W. Rixon , Josephine M. Cardarelli , Thomas D. Kempe , Scott R. Presnell , Mohan Srinivasan , Susan C. Wong , Guodong Chen , Hui Wei , Stanley R. Krystek , Lumelle A. Schneeweis , Paul O. Sheppard , Indrani Chakraborty
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- Agent Brian J. Walsh
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/24 ; C07K16/46 ; A61K39/00
Abstract:
The present invention relates to antagonizing the activity of IL-17A, IL-17F and IL-23 using bispecific antibodies that comprise a binding entity that is cross-reactive for IL-17A and IL-17F and a binding entity that binds IL-23p19. The present invention relates to novel bispecific antibody formats and methods of using the same.
Public/Granted literature
- US20180037645A1 IL-17A/F AND IL-23p19 BISPECIFIC ANTIBODIES AND METHODS OF USING THE SAME Public/Granted day:2018-02-08
Information query
