- 专利标题： Immunogenic compositions containing Escherichia coli H7 flagella and methods of use thereof
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申请号： US14949291申请日： 2015-11-23
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公开(公告)号： US10363297B2公开(公告)日： 2019-07-30
- 发明人: David Gally , Tom Nathan McNeilly , David George Emslie Smith , Chris Low , Arvind Kumar Mahajan , Stuart W. Naylor
- 申请人： The University Court of the University of Edinburgh , Moredun Research Institute , SRUC
- 申请人地址： GB Edinburgh GB Penicuik GB Edinburgh
- 专利权人： The University Court of the University of Edinburgh,Moredun Research Institute,SRUC
- 当前专利权人： The University Court of the University of Edinburgh,Moredun Research Institute,SRUC
- 当前专利权人地址： GB Edinburgh GB Penicuik GB Edinburgh
- 代理机构： Foley & Lardner LLP
- 代理商 Gilberto M. Villacorta; Jason N. Mock
- 优先权： GB0720250.0 20071017
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K39/108 ; C07K14/245 ; C07K16/12 ; A61K39/39
摘要：
Immunogenic compositions containing Escherichia coli 0157:H7 flagella including fusion proteins and methods using the immunogenic compositions are disclosed. Inducing an immune response in an animal to Escherichia coli O157:H7 flagella will result in prevention of colonization by Escherichia coli O157:H7 in the animal or a reduction in the amount of Escherichia coli O157:H7 infecting the animal. The immune composition will prevent or reduce the attachment of Escherichia coli 0157:H7 to cells within the animal.
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