Computer program products, methods, systems, apparatus, and computing entities for enhanced cargo screening capabilities are provided. In one embodiment, the method comprises: automatically and electronically executing a first screening procedure for capturing and storing first screening data comprising (a) an x-ray image and (b) first screening decontrol data; automatically and electronically determining whether at least a second screening procedure is required, the determination involving identifying at least one discrepancy between at least a portion of the first screening data and at least one predefined parameter; responsive to determining that the second screening is required, generating and transmitting one or more notifications configured to initiate the second screening procedure within a predetermined period of time; and responsive to determining that the at least second screening is not required, generating and transmitting a decontrol message configured to release the packages from further automated screening procedures.