A synchronization method and an apparatus for Device-to-Device (D2D) communication in a User Equipment (UE) are provided. The method includes comparing a reception power of a signal received from an evolved Node B (eNB) with a first reference power, if the reception power is less than the first reference power, generating and transmitting a synchronization signal for D2D communication by operating as a synchronization reference UE, comparing the reception power of a signal received from the eNB with a second reference power, and if the reception power is greater than or equal to the first reference power and less than the second reference power, relaying a synchronization signal received from the eNB by operating as a synchronization relaying UE.