Invention Grant
- Patent Title: Xylanase variants and polynucleotides encoding same
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Application No.: US15315539Application Date: 2015-06-25
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Publication No.: US10370682B2Publication Date: 2019-08-06
- Inventor: Brian R. Scott , Mark David Wogulis , Sven Pedersen , James Lavigne
- Applicant: NOVOZYMES A/S
- Applicant Address: DE Bagsvaerd
- Assignee: NOVOZYMES A/S
- Current Assignee: NOVOZYMES A/S
- Current Assignee Address: DE Bagsvaerd
- Agent David Fazzolare
- Priority: EP14173811 20140625
- International Application: PCT/US2015/037732 WO 20150625
- International Announcement: WO2015/200659 WO 20151230
- Main IPC: C12P19/14
- IPC: C12P19/14 ; C12N9/24 ; C12P19/34 ; C12P21/06 ; C12N1/20 ; C12P7/10 ; C12N15/52 ; C12N15/82

Abstract:
The present invention relates to xylanase variants, comprising an alteration at least at one position corresponding to position 87 of the polypeptide of SEQ ID NO: 3, wherein the variant has xylanase activity and has increased xylanase inhibitor tolerance compared to the xylanase of SEQ ID NO: 3; and i) wherein the variant has at least 75%, at least 80%, at least 85%, at least 90%, at least 95%, at least 96%, at least 97%, at least 98%, or at least 99%, but less than 100% sequence identity to the polypeptide of SEQ ID NO: 3; or ii) wherein the number of alterations is 1-20, e.g., 1-10 such as 1, 2, 3, 4, 5, 6, 7, 8, 9 or 10 alterations. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
Public/Granted literature
- US20170096687A1 XYLANASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME Public/Granted day:2017-04-06
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