Invention Grant
- Patent Title: Methods of using OX40 ligand encoding polynucleotides
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Application No.: US16207575Application Date: 2018-12-03
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Publication No.: US10379767B2Publication Date: 2019-08-13
- Inventor: Joshua P. Frederick , Ailin Bai
- Applicant: ModernaTX, Inc.
- Applicant Address: US MA Cambridge
- Assignee: ModernaTX, Inc.
- Current Assignee: ModernaTX, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Amy E. Mandragouras, Esq.; Ariana D. Harris
- Main IPC: A61K48/00
- IPC: A61K48/00 ; G06F3/06 ; A61K38/17 ; A61P35/00 ; A61K45/06 ; C07K14/705 ; G06F11/30
Abstract:
The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotide molecules comprising an mRNA encoding an OX40L polypeptide. Also provided is a method for activating T cells or increasing the number of NK cells in a subject in need thereof.
Public/Granted literature
- US20190114089A1 METHODS OF USING OX40 LIGAND ENCODING POLYNUCLEOTIDES Public/Granted day:2019-04-18
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