The present disclosure discloses a method and a device for elastic object deformation modeling. The method comprises: acquiring a static point cloud of the elastic object and dynamic point cloud sequences; establishing a simulation tetrahedral mesh model; driving the simulation tetrahedral mesh model to track the dynamic point cloud sequences, to obtain track deformation sequences; iteratively estimating material property coefficients and corresponding reference shapes of the elastic object; performing the following operations in each iteration: obtaining a reference shape corresponding to a current material property coefficient; driving the simulation tetrahedral mesh model to simulate the deformation from the same initial deformation according to the coefficient and the reference shape to obtain a simulation deformation sequences; calculating a positional deviation between the simulation deformation sequences and the track deformation sequences; and updating the material property coefficients in a direction in which the positional deviation is decreased; establishing an elastic object deformation model according to a material property coefficient under a minimum positional deviation and corresponding reference shape. The technical solution can establish a vivid elastic object deformation model.