A wearable electronic device may include a device body and a device band coupled to the device body for securing the device to a wrist of a user. The wearable electronic device may also include a wrist biometric sensor carried by one of the device body and the device band. The wrist biometric sensor may include biometric sensing pixels. The wearable electronic device may also include a processor coupled to the wrist biometric sensor and configured to cooperate with the biometric sensing pixels to acquire skin texture pattern images from adjacent portions of the user's wrist, and perform at least one authentication function based upon the skin texture pattern images.