Invention Grant
- Patent Title: Preparation of and formulation comprising a MEK inhibitor
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Application No.: US15842715Application Date: 2017-12-14
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Publication No.: US10398683B2Publication Date: 2019-09-03
- Inventor: Christoph Max Krell , Marian Misun , Daniel Andreas Niederer , Werner Heinz Pachinger , Marie-Christine Wolf , Daniel Zimmermann , Weidong Liu , Peter J. Stengel , Paul Nichols
- Applicant: Array BioPharma Inc.
- Applicant Address: US CO Boulder
- Assignee: Array BioPharma Inc.
- Current Assignee: Array BioPharma Inc.
- Current Assignee Address: US CO Boulder
- Agency: Fish & Richardson P.C.
- Main IPC: A61K31/4184
- IPC: A61K31/4184 ; A61K45/06 ; A61K47/26 ; A61K9/20 ; C07D235/08 ; C07D235/06 ; A61K47/12 ; A61K47/02 ; C30B29/54 ; C30B7/08 ; A61K47/38 ; A61K9/00
Abstract:
The present invention relates to processes for preparing 6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxyethyoxy)-amide, processes for preparing crystallized 6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxyethyoxy)-amide, and intermediates useful therefore. Also provided herein are pharmaceutical compositions comprising this crystallized compound.
Public/Granted literature
- US20180296533A1 PREPARATION OF AND FORMULATION COMPRISING A MEK INHIBITOR Public/Granted day:2018-10-18
Information query
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