A system, method, and computer program product are provided for blue-printing interference for mobile access in an unlicensed spectrum of a synchronous scheduled cellular access system. The system includes a cellular base station having a processor. The processor constructs and executes an intelligent measurement schedule of clients for uplink transmissions to obtain access measurements for the uplink transmissions. The intelligent measurement schedule is constructed for scalable access measurement overhead. The access measurements indicate interference dependencies between the clients. The processor estimates an interference topology and statistics of the interference topology, from the access measurements to form an interference blueprint. The processor adjusts the intelligent measurement schedule to overschedule the clients for the uplink transmissions to reduce spectrum utilization loss while minimizing client transmission collisions, based on the interference blueprint. The processor initiates the uplink transmissions for the clients in accordance with the adjusted intelligent measurement schedule.