The present disclosure provides a method and an apparatus for managing mobility of an MPTCP connection. The method includes: receiving a message that is sent by the source MPTCP agent and that carries an MPTCP context of UE; and saving the MPTCP context, and performing an MPTCP data transmission operation or an MPTCP management and control operation for the UE according to the saved MPTCP context. Embodiments of the present disclosure implement that, in a scenario in which both a source MPTCP agent and a destination MPTCP agent are deployed at a RAN side, when UE moves from a radio access device on which the source MPTCP agent is deployed to a radio access device on which the destination MPTCP agent is deployed, an MPTCP connection is maintained or the destination MPTCP agent can continue to perform a management and control operation.