Invention Grant
- Patent Title: 6-(5-hydroxy-1H-pyrazol-1-yl)nicotinamide inhibitors of PHD
-
Application No.: US15909801Application Date: 2018-03-01
-
Publication No.: US10407409B2Publication Date: 2019-09-10
- Inventor: Jason W. Brown , Melinda Davis , Anthony Ivetac , Benjamin Jones , Andre A. Kiryanov , Jon Kuehler , Marion Lanier , Joanne Miura , Sean Murphy , Xiaolun Wang
- Applicant: Takeda Pharmaceutical Company Limited
- Applicant Address: JP Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agent Matthew J. Russo; David M. Stemerick
- Main IPC: C07D401/04
- IPC: C07D401/04 ; C07D401/14 ; C07D405/14 ; C07D413/14 ; C07D417/14 ; A61K31/4439 ; A61K31/4545 ; A61K31/5377 ; A61K31/496 ; A61K31/551 ; C07D491/107 ; C07D471/08 ; C07D487/06 ; C07D487/10 ; C07D491/10 ; A61K31/444 ; A61K31/4985 ; A61K31/5513 ; C07D487/04
Abstract:
The present invention provides compounds of the formula: which are useful as inhibitors of PHD, pharmaceutical compositions thereof, methods for treatment of conditions associated with HIF, processes for making the compounds and intermediates thereof.
Public/Granted literature
- US20180186772A1 6-(5-HYDROXY-1H-PYRAZOL-1-YL)NICOTINAMIDE INHIBITORS OF PHD Public/Granted day:2018-07-05
Information query
