Invention Grant
- Patent Title: Bicyclic [4,6,0] hydroxamic acids as HDAC inhibitors
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Application No.: US16199489Application Date: 2018-11-26
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Publication No.: US10407418B2Publication Date: 2019-09-10
- Inventor: Xiaozhang Zheng , Pui Yee Ng , Aleksandra Rudnitskaya , David R. Lancia, Jr.
- Applicant: FORMA Therapeutics, Inc.
- Applicant Address: US MA Watertown
- Assignee: Forma Therapeutics, Inc.
- Current Assignee: Forma Therapeutics, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Choate, Hall & Stewart LLP
- Agent Michael A. Shinall; Erica M. D'Amato
- Main IPC: C07D245/06
- IPC: C07D245/06 ; C07D471/04 ; C07D487/04 ; C07D413/06 ; C07D267/22
![Bicyclic [4,6,0] hydroxamic acids as HDAC inhibitors](/abs-image/US/2019/09/10/US10407418B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to inhibitors of zinc-dependent histone deacetylases (HDACs) useful in the treatment of diseases or disorders associated with HDAC6, having a Formulae I or Formula II: where R, L, X1, X2, X3, X4, X5, Y1, Y2, Y3, and Y4 are described herein.
Public/Granted literature
- US20190092762A1 BICYCLIC [4,6,0] HYDROXAMIC ACIDS AS HDAC INHIBITORS Public/Granted day:2019-03-28
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