- 专利标题： Amorphous vortioxetine and salts thereof
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申请号： US14916075申请日： 2014-09-30
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公开(公告)号： US10414741B2公开(公告)日： 2019-09-17
- 发明人: Shri Prakash Dhar Dwivedi , Kumar Kamlesh Singh , Jitendra Maganbhai Gajera , Dinesh Kumar Raikwar , Brij Khera
- 申请人： CADILA HEALTHCARE LIMITED
- 申请人地址： IN Ahmedabad, Gujarat
- 专利权人： CADILA HEALTHCARE LIMITED
- 当前专利权人： CADILA HEALTHCARE LIMITED
- 当前专利权人地址： IN Ahmedabad, Gujarat
- 代理机构： Nixon & Vanderhye P.C.
- 优先权： IN3121/MUM/2013 20130930
- 国际申请： PCT/IN2014/000633 WO 20140930
- 国际公布： WO2015/044963 WO 20150402
- 主分类号： C07D295/096
- IPC分类号： C07D295/096
摘要：
The present invention relates to an amorphous vortioxetine and salts thereof. In particular, the invention relates to a process for the preparation of an amorphous vortioxetine hydrobromide. Further, the invention also relates to a process for preparation of amorphous vortioxetine free base. The invention also relates to pharmaceutical compositions comprising an amorphous vortioxetine or hydrobromide salt thereof for oral administration for treatment of major depressive disorder (MDD) and generalized anxiety disorder (GAD).
公开/授权文献
- US20160214949A1 AN AMORPHOUS VORTIOXETINE AND SALTS THEREOF 公开/授权日：2016-07-28
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