- 专利标题： Indolizine compounds, a process for their preparation and pharmaceutical compositions containing them
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申请号： US15906389申请日： 2018-02-27
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公开(公告)号： US10414754B2公开(公告)日： 2019-09-17
- 发明人: Arnaud Le Tiran , Thierry Le Diguarher , Jérôme-Benoît Starck , Jean-Michel Henlin , Guillaume De Nanteuil , Olivier Geneste , James Edward Paul Davidson , James Brooke Murray , I-Jen Chen
- 申请人： LES LABORATOIRES SERVIER , VERNALIS (R&D) LTD
- 申请人地址： FR Suresnes GB Winnersh Berkshire
- 专利权人： LES LABORATOIRES SERVIER,VERNALIS (R&D) LTD
- 当前专利权人： LES LABORATOIRES SERVIER,VERNALIS (R&D) LTD
- 当前专利权人地址： FR Suresnes GB Winnersh Berkshire
- 代理机构： Hueschen and Sage
- 优先权： FR1357265 20130723
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; C07D471/04 ; A61K31/4725 ; A61K31/4985 ; C07D487/04 ; C07D519/00 ; A61K45/06 ; A61K31/475 ; A61K31/5377 ; A61K9/20 ; A61K31/4709 ; A61N5/10
摘要：
Compounds of formula (I) wherein Ra, Rb, Rc, Rd, T, R3, R4, R5, X, Y and Het are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.
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