A data driver and display panel are disclosed. The data driver is applicable to providing image data to be displayed to a plurality of data lines. The data driver includes: a data processing unit, a driving unit, and at least two sets of data outputs. The data processing unit is configured to receive and store one frame of image data to be displayed. The driving unit is to output at least two sets of data voltages having different driving capacities according to the image data. Each of the at least two sets of data outputs includes a plurality of data outputs, and each set is connected to pixels in two areas with a different distance from the data driver. The driving unit provides the at least two sets of data voltages having different driving capabilities to the at least two sets of data outputs.