Invention Grant
- Patent Title: CFTR MRNA compositions and related methods and uses
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Application No.: US15625648Application Date: 2017-06-16
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Publication No.: US10420791B2Publication Date: 2019-09-24
- Inventor: Michael Heartlein , Braydon Charles Guild , Frank DeRosa , Carsten Rudolph , Christian Plank , Lianne Smith
- Applicant: Translate Bio, Inc. , Ethris GmbH
- Applicant Address: US MA Lexington
- Assignee: Translate Bio, Inc.
- Current Assignee: Translate Bio, Inc.
- Current Assignee Address: US MA Lexington
- Agency: Proskauer Rose LLP
- Agent Fangli Chen; Julio J. Mendez
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N15/63 ; C07H21/04 ; A61K31/713 ; C07K14/705 ; A61K31/7105 ; A61K31/7115 ; A61K9/00 ; A61K9/51 ; A61K9/127 ; C12N9/14 ; A61K47/69 ; C07H21/02 ; C07K14/47 ; C12N15/88
Abstract:
The present invention is particularly useful for treating cystic fibrosis. The disclosure concerns method and compositions for treating cystic fibrosis. The method comprises inducing CFTR expression in epithelial cells in a lung of a mammal by contacting the epithelial cells in the lung of the mammal with a composition, where the composition is a pharmaceutical composition comprising in vitro transcribed mRNA.
Public/Granted literature
- US20180015116A1 CFTR MRNA COMPOSITIONS AND RELATED METHODS AND USES Public/Granted day:2018-01-18
Information query
