- 专利标题： Sulfur-containing compounds targeting vesicular acetylcholine transporter
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申请号： US15620263申请日： 2017-06-12
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公开(公告)号： US10421722B2公开(公告)日： 2019-09-24
- 发明人: Zhude Tu , Zonghua Luo , Hui Liu , Hongjun Jin , Stanley M. Parsons
- 申请人： Zhude Tu , Zonghua Luo , Hui Liu , Hongjun Jin , Stanley M. Parsons
- 申请人地址： US MO St. Louis US CA Oakland
- 专利权人： Washington University,The Regents of the University of California
- 当前专利权人： Washington University,The Regents of the University of California
- 当前专利权人地址： US MO St. Louis US CA Oakland
- 代理机构： Stinson LLP
- 主分类号： A61K9/14
- IPC分类号： A61K9/14 ; C07D211/32 ; A61K51/04 ; A61B6/03 ; C07B59/00
摘要：
The present invention generally relates to various compounds that are useful as vesicular acetylcholine transporter (VAChT) ligands. The invention further relates to methods of using these compounds and their radiolabeled analogs for the detection of neurodegenerative diseases including Parkinson's disease (PD), and Alzheimer's disease (AD).
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