Invention Grant
- Patent Title: Lipids and lipid compositions for the delivery of active agents
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Application No.: US15104723Application Date: 2014-12-17
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Publication No.: US10426737B2Publication Date: 2019-10-01
- Inventor: Luis Brito , Delai Chen , Gabriel Grant Gamber , Andrew Geall , Kevin Love , Thomas Zabawa , Frederic Zecri
- Applicant: Novartis AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agency: Brinks Gilson & Lione
- International Application: PCT/US2014/070891 WO 20141217
- International Announcement: WO2015/095346 WO 20150625
- Main IPC: C07C219/06
- IPC: C07C219/06 ; C07C219/16 ; C07C229/12 ; C07C235/08 ; C07C323/52 ; A61K9/51 ; C07D319/06 ; C07D233/60 ; C07D207/12 ; C07D207/16 ; C07D211/22 ; C07D295/088 ; C07D211/62 ; A61K47/18 ; A61K9/127 ; A61K31/7105 ; A61K31/713 ; C12N15/88 ; A61K38/18 ; A61K38/22 ; A61K39/12 ; C07D211/06 ; C07D211/46 ; C07D233/64 ; C07D295/13 ; C12N7/00 ; C12N15/113 ; A61K39/00
Abstract:
This invention provides for a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein R1-R3, n, p, L1 and L2 are defined herein. The compounds of formula (I) and pharmaceutically acceptable salts thereof are cationic lipids useful in the delivery of biologically active agents to cells and tissues.
Public/Granted literature
- US20160317458A1 Lipids and Lipid Compositions for the Delivery of Active Agents Public/Granted day:2016-11-03
Information query
