Invention Grant
- Patent Title: Cytotoxic antibody
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Application No.: US15101586Application Date: 2014-12-02
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Publication No.: US10428312B2Publication Date: 2019-10-01
- Inventor: Boon Hwa Andre Choo , Jiyun Zheng
- Applicant: Agency for Science, Technology and Research
- Applicant Address: SG Singapore
- Assignee: Agency for Science, Technology and Research
- Current Assignee: Agency for Science, Technology and Research
- Current Assignee Address: SG Singapore
- Agency: Choate, Hall & Stewart LLP
- Priority: SG201308964 20131203
- International Application: PCT/SG2014/000570 WO 20141202
- International Announcement: WO2015/084262 WO 20150611
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12N5/16 ; C07K16/18 ; C07K16/44 ; C12N5/00
Abstract:
An antibody that binds a glycosylated protein is disclosed, wherein the glycosylation comprises the glycan motif Fucα1-2Galβ1-3GlcNAc1-3Galβ1 or Fucα1-2Galβ1-3GlcNAc. Antibodies that are cytotoxic against undifferentiated pluripotent cells are also disclosed.
Public/Granted literature
- US20170002331A1 CYTOTOXIC ANTIBODY Public/Granted day:2017-01-05
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