The invention provides a pixel array, including N rows and M columns of pixel units, wherein each pixel unit includes two sub-pixels, two adjacent pixel units in the same row include sub-pixels of three colors including a red sub-pixel, a green sub-pixel and a blue sub-pixel, every two adjacent sub-pixels in the same row have different colors, in the pixel array, all the sub-pixels have the same shape, every two adjacent green sub-pixels are provided with a sub-pixel of other color therebetween, and every two adjacent blue sub-pixels are provided with three sub-pixels of other colors therebetween. The invention also provides a display device, a driving method and a driving device. Employing the pixel array of the invention, an image is displayed with a higher visual resolution, and a mask plate for manufacturing the pixel array has a larger minimal size, and the pixel array is manufactured with high yield.