Invention Grant
- Patent Title: Trans-base tunnel reader for sequencing
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Application No.: US15417903Application Date: 2017-01-27
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Publication No.: US10442771B2Publication Date: 2019-10-15
- Inventor: Stuart Lindsay , Peiming Zhang
- Applicant: ARIZONA BOARD OF REGENTS on behalf of ARIZONA STATE UNIVERSITY
- Applicant Address: US AZ Scottsdale
- Assignee: ARIZONA BOARD OF REGENTS on behalf of ARIZONA STATE UNIVERSITY
- Current Assignee: ARIZONA BOARD OF REGENTS on behalf of ARIZONA STATE UNIVERSITY
- Current Assignee Address: US AZ Scottsdale
- Agency: Schwabe Williamson & Wyatt, P.C.
- Main IPC: C07D235/24
- IPC: C07D235/24 ; G01N33/487 ; G01N27/447 ; C12Q1/6869

Abstract:
The present invention is directed to systems, devices and methods for identifying biopolymers, such as strands of DNA, as they pass through a constriction such as a carbon nanotube nanopore. More particularly, the invention is directed to such systems, devices and methods in which a newly translocated portion of the biopolymer forms a temporary electrical circuit between the nanotube nanopore and a second electrode, which may also be a nanotube. Further, the invention is directed to such systems, devices and methods in which the constriction is provided with a functionalized unit which, together with a newly translocated portion of the biopolymer, forms a temporary electrical circuit that can be used to characterize that portion of the biopolymer.
Public/Granted literature
- US20170204066A1 NANOPORE BASED SEQUENCER Public/Granted day:2017-07-20
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