Invention Grant
- Patent Title: Isoxazole analogs as FXR agonists and methods of use thereof
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Application No.: US15724919Application Date: 2017-10-04
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Publication No.: US10450306B2Publication Date: 2019-10-22
- Inventor: Jun Ma , Guoqiang Wang , Bin Wang , Xuechao Xing , Ruichao Shen , Jing He , Yat Sun Or
- Applicant: Enanta Pharmaceuticals, Inc.
- Applicant Address: US MA Watertown
- Assignee: Enanta Pharmaceuticals, Inc.
- Current Assignee: Enanta Pharmaceuticals, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Elmore Patent Group, P.C.
- Agent Edgar W. Harlan; Carolyn S. Elmore, Esq.
- Main IPC: C07D261/08
- IPC: C07D261/08 ; C07D413/12 ; C07D413/14 ; C07D417/14

Abstract:
The present invention provides compounds of Formula I, pharmaceutical compositions comprising these compounds and methods of using these compounds to prevent or treat FXR-mediated or TGR5-mediated diseases or conditions.
Public/Granted literature
- US20180099957A1 ISOXAZOLE ANALOGS AS FXR AGONISTS AND METHODS OF USE THEREOF Public/Granted day:2018-04-12
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